Amlodipine, initially approved by the FDA in 1987, is a medication that belongs to a class of drugs known as calcium channel blockers. It is primarily used to treat high blood pressure (hypertension) and certain types of chest pain (angina). Amlodipine works by relaxing and widening the blood vessels, which helps to improve blood flow and reduce blood pressure.
Removal of impurity standards from API manufacturing is an integral part of drug manufacturing. Toref has specialization in synthesis / supply of pharmacopoeia impurities, process impurities, isolation and identification of unknown impurities of Amlodipine to all pharmaceutical companies globally. All ready-to-ship Amlodipine Impurities are tabulated below:
| Product Name | CAS No. | Molecular Formula |
| Amlodipine EP Impurity D Oxalate | 1216406-90-4 | C22H25ClN2O9 |
| Amlodipine EP Impurity A | 88150-62-3 | C28H27ClN2O7 |
| Amlodipine EP Impurity F | 140171-66-0 | C19H23ClN2O5 |
| Amlodipine EP Impurity H | 318465-73-5 | C28H29ClN2O8 |
| Amlodipine Impurity 48 | 39562-06-6 | C18H20ClNO4 |
| Amlodipine EP Impurity E | 140171-65-9 | C21H27ClN2O5 |
| Amlodipine EP Impurity G | 43067-01-2 | C17H18ClN04 |
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