Carvedilol is a medication that belongs to a class of drugs called beta-blockers. It is primarily used to treat high blood pressure (hypertension) and heart failure. Carvedilol works by blocking certain receptors in the body, specifically beta receptors, which helps to reduce the workload on the heart and lower blood pressure.
Carvedilol has dual actions, as it not only acts as a non-selective beta blocker but also possesses alpha-blocking activity. This combination of actions allows carvedilol to widen the blood vessels and improve blood flow, while also reducing the heart’s workload and oxygen demand.
In addition to its use for hypertension and heart failure, carvedilol may also be prescribed for the management of angina (chest pain) and to reduce the risk of heart attacks in individuals who have had a heart attack in the past.
Removal of impurity standards from API manufacturing is an integral part of drug manufacturing. Toref has specialization in synthesis / supply of pharmacopoeia impurities, process impurities, isolation and identification of unknown impurities of Carvedilol to all pharmaceutical companies globally. All ready-to-ship Carvedilol Impurities are tabulated below:
| Product Name | CAS No. | Molecular Formula |
| Carvedilol Impurity 2 | 1198090-71-9 | C18H17NO3 |
| Carvedilol Impurity 4 | 26646-63-9 | C17H15NO4 |
| Carvedilol Impurity 19 | 72956-44-6 | C23H24N2O4 |
| Carvedilol Impurity 17 | 18181-71-0 | C9H12O3 |
| Carvedilol EP Impurity A | 1198090-73-1 | C36H43N3O7 |
| Carvedilol Impurity 26 | 553-45-7 | C16H18O4 |
| Carvedilol Impurity 20 | 123119-89-1 | C15H15NO3 |
| Carvedilol EP Impurity C | 72955-94-3 | C31H32N2O4 |
| Carvedilol EP Impurity A | 1198090-73-1 | C36H43N3O7 |
| Carvedilol Impurity 16 | 1276477-91-8 | C27H22N2O3 |
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