Acotiamide Impurity LGK

Cat. No.REF-A39019
CAS. No.1243244-14-5
Molecular FormulaC23H20N6O
Molecular Weight396.45 g/mol
Inventory StatusPlease enquire.

描述

Cat. No.REF-A39019
CAS. No.1243244-14-5
Molecular FormulaC23H20N6O
Molecular Weight396.45 g/mol
Synonyms2-(2′,3-dimethyl-[2,4′-bipyridin]-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide; Acotiamide Impurity 43
AppearanceWhite solid
Storage TemperatureN/A
ApplicationsAcotiamide Impurity LGK is a selective and orally bioavailable Porcupine inhibitor under development for the treatment of cancers that are driven by the Wnt pathway in a Wnt ligand-dependent manner. LGK974 was shown to induce tumor regression in a Wnt-driven murine tumor model.

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