Description
Cat. No. | REF-A39019 |
CAS. No. | 1243244-14-5 |
Molecular Formula | C23H20N6O |
Molecular Weight | 396.45 g/mol |
Synonyms | 2-(2′,3-dimethyl-[2,4′-bipyridin]-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide; Acotiamide Impurity 43 |
Appearance | White solid |
Storage Temperature | N/A |
Applications | Acotiamide Impurity LGK is a selective and orally bioavailable Porcupine inhibitor under development for the treatment of cancers that are driven by the Wnt pathway in a Wnt ligand-dependent manner. LGK974 was shown to induce tumor regression in a Wnt-driven murine tumor model. |
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