Bictegravir

Cat. No.REF-B81001
CAS. No.1611493-60-7
Molecular FormulaC21H18F3N3O5
Molecular Weight449.39 g/mol
Inventory StatusPlease enquire.

描述

Cat. No.REF-B81001
CAS. No.1611493-60-7
Molecular FormulaC21H18F3N3O5
Molecular Weight449.39 g/mol
Synonyms(2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
AppearanceWhite to off-white solid
Storage Temperature-20°C
ApplicationsBictegravir, is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM. Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection. It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet. Bictegravir is indicated in the management of HIV-1 infection in patients not previously treated with antiretroviral therapy.

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